| 1 | Episcopal Academy | Newtown Square, Pennsylvania |
| 2 | Emmaus High School | Emmaus, Pennsylvania |
| 3 | The Hill School | Pottstown, Pennsylvania |
| 4 | Wyoming Seminary | Kingston, Pennsylvania |
| 5 | Palmyra Area High School | Palmyra, Pennsylvania |
| 6 | Lower Dauphin High School | Hummelstown, Pennsylvania |
| 7 | Wilson High School | West Lawn, Pennsylvania |
| 8 | Wyoming Area High School | Exeter, Pennsylvania |
| 9 | Wyoming Valley West High School | Plymouth, Pennsylvania |
| 10 | Oley Valley High School | Oley, Pennsylvania |
| 11 | Twin Valley High School | Elverson, Pennsylvania |
| 12 | Conestoga High School | Berwyn, Pennsylvania |
| 13 | Villa Maria Academy | Malvern, Pennsylvania |
| 14 | Hershey High School | Hershey, Pennsylvania |
| 15 | Methacton High School | Eagleville, Pennsylvania |
| 16 | Central Bucks East High School | Doylestown, Pennsylvania |
| 17 | Central Dauphin HIgh School | Harrisburg, Pennsylvania |
| 18 | Archbishop Carroll High School | Radnor, Pennsylvania |
| 19 | Greenwood High School | Millerstown, Pennsylvania |
| 20 | Gwynedd Mercy Academy High School | Gwynedd Valley, Pennsylvania |
| | |
| OC | Academy of Notre Dame de Namur | Villanova, Pennsylvania |
| OC | Fleetwood Area High School | Fleetwood, Pennsylvania |
| OC | Downingtown West High School | Downingtown, Pennsylvania |
| OC | Easton Area High School | Easton, Pennsylania |
| OC | East Pennsboro High School | Enola, Pennsylvania |
| OC | Garnet Valley High School | Glen Mills, Pennsylvania |
| OC | Penn Manor High School | Millersville, Pennsylvania |
| OC | Plymouth Whitemarsh High School | Plymouth Meeting, Pennsylvania |
| OC | Selinsgrove Area High School | Selinsgrove, Pennsylvania |
| OC | Souderton Area High School | Souderton, Pennsylvania |
2021 PENNSYLVANIA REGION HIGH SCHOOL
