| 1 | Episcopal Academy | Newtown Square, Pennsylvania | 20-1-1 | 7 | PAISAA Champions, Inter-AC Champions |
| 2 | Wilson High School | West Lawn, Pennsylvania | 25-3-0 | 4 | AAA State Champions, District III AAA Runner-Up |
| 3 | Lower Dauphin High School | Hummelstown, Pennsylvania | 23-1-3 | 1 | AAA State Runner-Up, District III AAA Champions |
| 4 | The Hill School | Pottstown, Pennsylvania | 17-3-0 | 5 | PAISAA Runner-Up, MAPL Champions |
| 5 | Wyoming Seminary | Kingston, Pennsylvania | 23-2-0 | 10 | A State Champions, District II A Champions |
| 6 | Wyoming Valley West High School | Plymouth, Pennsylvania | 16-3-1 | OC | AA State Champions, District II 2A Champions |
| 7 | Palmyra Area High School | Palmyra, Pennsylvania | 22-4-0 | 2 | AA State Runner-Up, District III AA Champions |
| 8 | Oley Valley High School | Oley, Pennsylvania | 25-2-0 | 3 | A State Runner-Up, District III A Runner-Up |
| 9 | Emmaus High School | Emmaus, Pennsylvania | 26-1-0 | 8 | AAA State Semifinalist, District XI AAA Champions |
| 10 | Hershey High School | Hershey, Pennsylvania | 18-7-0 | 6 | AAA State Semifinalist, District III AAA Semifinalist, 3rd Place through Playbacks |
| 11 | Greenwood High School | Millerstown, Pennsylvania | 19-2-2 | 11 | A State Semifinalist, District III A Champions |
| 12 | Academy of Notre Dame de Namur | Villanova, Pennsylvania | 16-6-1 | 9 | PAISAA Semifinalist |
| 13 | New Hope Solebury High School | New Hope, Pennsylvania | 22-1-0 | 12 | A State Quarterfinalist, District 1 1A Champions |
| 14 | Wyoming Area High School | Exeter, Pennsylvania | 18-3-0 | 16 | A State Semifinalist, District II A Runner-Up |
| 15 | Merion Mercy Academy | Merion Station, Pennsylvania | 19-4-1 | 15 | AA State Quarterfinalist, District 1 2A Champions |
| 16 | Villa Maria Academy | Malvern, Pennsylvania | 13-10-0 | OC | AA State Semifinalist, District I 2A Semifinalist, 3rd Place through Playbacks |
| 17 | Gwynedd Mercy Academy High School | Gwynedd Valley, Pennsylvania | 15-6-0 | 20 | District I 2A Quarterfinalist |
| 18 | Central Dauphin High School | Harrisburg, Pennsylvania | 16-8-0 | 18 | AAA State Quarterfinalist, District III AAA Semifinalist, 4th Place through Playbacks |
| 19 | Downingtown West High School | Downingtown, Pennsylvania | 17-6-0 | 14 | AAA State First Round, District I 3A Champions |
| 20 | East Pennsboro High School | Enola, Pennsylvania | 17-5-0 | 19 | AA State First Round, District III AA Runner-Up |
| OC | Central Bucks East High School | Doylestown, Pennsylvania | 15-5-0 | OC | District I 3A Quarterfinalist |
| OC | Easton Area High School | Easton, Pennsylvania | 18-5-0 | NR | AAA State Quarterfinalist, District XI AAA Runner-Up |
| OC | Garnet Valley High School | Glen Mills, Pennsylvania | 21-2-0 | OC | AAA State First Round, District I 3A Quarterfinalist, 5th Place through Playbacks |
| OC | Mount Saint Joseph High School | Flourtown, Pennsylvania | 14-9-0 | OC | AA State First Round, District I 2A Quarterfinalist, 5th Place through Playbacks |
| OC | Northern York High School | Dillsburg, Pennsylvania | 20-4-0 | 17 | AA State Quarterfinalist, District III AA Semifinalist, 4th Place through Playbacks |
| OC | Owen J. Roberts High School | Pottstown, Pennsylvania | 21-4-0 | 13 | AAA State Quarterfinalist, District I 3A Semifinalist, 4th Place through Playbacks |
| OC | Penn Manor High School | Millersville, Pennsylvania | 14-5-0 | OC | District III AAA Quarterfinalist |
| OC | Perkiomen Valley High School | Collegeville, Pennsylvania | 19-5-1 | OC | AAA State Quarterfinalist, District I 3A Semifinalist, 3rd Place through Playbacks |
| OC | Plymouth Whitemarsh High School | Plymouth Meeting, Pennsylvania | 20-3-0 | OC | AAA State First Round, District I 3A Runner-Up |
| OC | Radnor High School | Wayne, Pennsylvnia | 16-4-0 | OC | District I 2A Quarterfinalist |
| OC | Selinsgrove Area High School | Selinsgrove, Pennsylvania | 16-4-0 | OC | AA State Quarterfinalist, District IV AA Champions |
| OC | Souderton High School | Souderton, Pennsylvania | 18-5-0 | OC | AAA State First Round, District I 3A Quarterfinalist, 6th Place through Playbacks |
| OC | Twin Valley High School | Elverson, Pennsylvania | 18-9-0 | OC | AA State Semifinalist, District III AA Semifinalist, 3rd Place through Playbacks |
| OC | Upper Perkiomen High School | Pennsburg, Pennsylvania | 18-6-0 | NR | AA State Quarterfinalist, District I AA Runner-Up |
2019 PENNSYLVANIA REGION HIGH SCHOOL
